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Cajeput oil (Melaleuca quinquenervia)
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Cajeput oil/Drug Interactions:- AnestheticsAnesthetics: Based on a study using cocaine, cajeput oil may intensify local anesthetic power when combined with other anesthetics (5).
- AntibioticsAntibiotics: Based on an in vitro study, extracts from Melalleuce quinquenervia [sic] may have antibacterial activity when combined with selected antibiotics (6).
- Antidiabetic agentsAntidiabetic agents: Based on an animal study, Melaleuca quinquenervia leaves may have a significant dose-dependent (35-70mg/kg) hypoglycemic effect (1).
- AntihistaminesAntihistamines: Based on an in vitro study, chloroform and methanol extracts of Melaleuca quinquenervia fruits may have antihistamine effects (7).
- AntihypertensivesAntihypertensives: Based on an in vitro study, Melaleuca quinquenervia leaves may either inhibit vascular contractile responses or significantly relax contractions, possibly by using nitric oxide as a mediator (2).
- AntioxidantsAntioxidants: Based on an in vitro study, Melaleuca quinquenervia (Clav.) S. T. Blake may have antioxidant activity (1).
- Antiulcer agentsAntiulcer agents: Based on an in vitro study, Melaleuca quinquenervia may inhibit the growth of Helicobacter pylori (4).
- Antiviral agentsAntiviral agents: Based on a mouse HSV-1 infection assay, the fruit of Melaleuca quinquenervia may inhibit herpes simplex I (3).
- Cytochrome P450 metabolized agentsCytochrome P450 metabolized agents: Based on an in vitro study, Melaleuca quinquenervia leaf may have a time-dependent increase of CYP2D6 inhibition (9).
- Hypertensive drugsHypertensive drugs: Based on in vitro study, Melaleuca quinquenervia leaves may either inhibit vascular contractile responses or significantly relax contractions, possibly by using nitric oxide as a mediator (2).
- Mosquito repellentsMosquito repellents: Based on a study using humans, cajeput may have mosquito repellent effects against Aedes aegypti (Linnaeus), Anopheles stephensi (Liston), and Culex quinquefasciatus (Say) (8).
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Cajeput oil/Herb/Supplement Interactions:- AnestheticsAnesthetics: Based on a study using cocaine, cajeput oil may intensify local anesthetic power when combined with other anesthetics (5).
- AntibacterialsAntibacterials: Based on an in vitro study, extracts from Melalleuce quinquenervia [sic] may have antibacterial activity when combined with selected antibiotics (6).
- AntihistaminesAntihistamines: Based on an in vitro study, chloroform and methanol extracts of Melaleuca quinquenervia fruits may have antihistamine effects (7).
- AntioxidantsAntioxidants: Based on an in vitro study, Melaleuca quinquenervia (Clav.) S. T. Blake may have antioxidant activity (1).
- Antiulcer agentsAntiulcer agents: Based on an in vitro study, Melaleuca quinquenervia may inhibit the growth of Helicobacter pylori (4).
- AntiviralsAntivirals: Based on a mouse HSV-1 infection assay, the fruit of Melaleuca quinquenervia may inhibit herpes simplex I (3).
- Cytochrome P450 metabolized herbs and supplementsCytochrome P450 metabolized herbs and supplements: Based on an in vitro study, Melaleuca quinquenervia leaf may have a time-dependent increase of CYP2D6 inhibition (9).
- HypertensivesHypertensives: Based on an in vitro study, Melaleuca quinquenervia leaves may either inhibit vascular contractile responses or significantly relax contractions, possibly by using nitric oxide as a mediator (2).
- HypoglycemicsHypoglycemics: Based on an animal study, Melaleuca quinquenervia leaves may have a significant dose-dependent (35-70mg/kg) hypoglycemic effect (1).
- HypotensivesHypotensives: Based on an in vitro study, Melaleuca quinquenervia leaves may either inhibit vascular contractile responses or significantly relax contractions, possibly by using nitric oxide as a mediator (2).
- Mosquito repellentsMosquito repellents: Based on a study using humans, cajeput may have mosquito repellent effects against Aedes aegypti (Linnaeus), Anopheles stephensi (Liston), and Culex quinquefasciatus (Say) (8).
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Cajeput oil/Food Interactions:- Insufficient available evidence.
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Cajeput oil/Lab Interactions:- BUNBUN: Based on an animal study, Melaleuca quinquenervia leaves may reduce elevated blood urea nitrogen (BUN) levels in diabetics (1).
- Helicobacter pylori testsHelicobacter pylori tests: Based on an in vitro study, Melaleuca quinquenervia may inhibit the growth of Helicobacter pylori (4).
- Serum glucose levelsSerum glucose levels: Based on an animal study, Melaleuca quinquenervia leaves may have a significant dose-dependent (35-70mg/kg) hypoglycemic effect (1).
- Serum levels of cytochrome P450 metabolized drugs or herbsSerum levels of cytochrome P450 metabolized drugs or herbs: Based on an in vitro study, Melaleuca quinquenervia leaf may have a time-dependent increase of CYP2D6 inhibition (9).
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Copyright © 2011 Natural Standard (www.naturalstandard.com)
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The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.
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