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Mist bredina (Bridelia spp.)
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Bridelia species/Drug Interactions:- AntibioticsAntibiotics: In vitro, extracts from many species of Bridelia exhibited antibacterial activity (4; 6; 18; 12; 13; 5; 29; 14).
- Anticoagulants and antiplateletsAnticoagulants and antiplatelets: In animal research, extracts of Bridelia ferruginea exhibited antithrombotic effects (17).
- Antidiabetic agentsAntidiabetic agents: According to secondary sources, Bridelia has been used traditionally for its potential antidiabetic effects. Mist bredina is a decoction prepared from Bridelia ferruginea that has purportedly been used for management of diabetes mellitus type 2. Clinical evidence for this therapy is lacking.
- AntidiarrhealsAntidiarrheals: In in vitro and animal research, extracts of Bridelia micrantha bark demonstrated antidiarrheal activity (19).
- AntifungalsAntifungals: In laboratory research, extracts of the stem bark of Bridelia retusa showed antifungal activity against Cladosporium cladosporioides at very low concentrations (7).
- AntihypertensivesAntihypertensives: In animal research, preparations of the leaves of Bridelia atroviridis caused a decrease in arterial pressure (24).
- Anti-inflammatory agentsAnti-inflammatory agents: Extracts from many species of Bridelia have exhibited anti-inflammatory activity in vitro and in animal studies (2; 9; 11; 10).
- Antimalarial agentsAntimalarial agents: In vitro, extracts of the root and stem of Bridelia cathartica caused a 50% inhibition of Plasmodium falciparum growth (20).
- EstrogensEstrogens: In animal and in vitro research, some constituents of the extracts of Bridelia ferruginea had estrogenic activity (25).
- Heart rate-regulating agentsHeart rate-regulating agents: In animal research, preparations of the leaves of Bridelia atroviridis caused a decrease in heart rate (24).
- ImmunomodulatorsImmunomodulators: Based on in vitro evidence, an extract from Bridelia ferruginea stem bark may dose-dependently inhibit the classical and the alternative pathways of the complement system (26).
- Uterotonic agentsUterotonic agents: In animal research, Bridelia atroviridis had a potent uterotonic action (28).
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Bridelia species/Herb/Supplement Interactions:- AntiarrhythmicsAntiarrhythmics: In animal research, preparations of the leaves of Bridelia atroviridis caused a decrease in heart rate (24).
- AntibacterialsAntibacterials: In vitro, extracts from many species of Bridelia exhibited antibacterial activity (4; 6; 18; 12; 13; 5; 29; 14).
- Anticoagulants and antiplateletsAnticoagulants and antiplatelets: In animal research, extracts of Bridelia ferruginea exhibited antithrombotic effects (17).
- AntidiarrhealsAntidiarrheals: In in vitro and animal research, extracts of Bridelia micrantha bark demonstrated antidiarrheal activity (19).
- AntifungalsAntifungals: In laboratory research, extracts of the stem bark of Bridelia retusa showed antifungal activity against Cladosporium cladosporioides at very low concentrations (7).
- Anti-inflammatory herbsAnti-inflammatory herbs: Extracts from many species of Bridelia have exhibited anti-inflammatory activity in vitro and in animal studies (2; 9; 11; 10).
- Antimalarial herbs and supplementsAntimalarial herbs and supplements: In vitro, extracts of the root and stem of Bridelia cathartica caused a 50% inhibition of Plasmodium falciparum growth (20).
- AntioxidantsAntioxidants: In vitro, constituents of Bridelia ferruginea exhibited xanthine oxidase-inhibiting and superoxide-scavenging activity at micromolar concentrations (15).
- HypoglycemicsHypoglycemics: According to secondary sources, Bridelia has been used traditionally for its potential antidiabetic effects. Mist bredina is a decoction prepared from Bridelia ferruginea that has purportedly been used for management of diabetes mellitus type 2. Clinical evidence for this therapy is lacking.
- HypotensivesHypotensives: In animal research, preparations of the leaves of Bridelia atroviridis caused a decrease of arterial pressure (24).
- ImmunomodulatorsImmunomodulators: Based on in vitro evidence, an extract from Bridelia ferruginea stem bark may dose-dependently inhibit the classical and the alternative pathways of the complement system (26).
- IronIron: The iron content in the root bark of Bridelia cathartica and its decoction (boiled extract) compared well with those found in edible leafy vegetables (3). Prominent iron contents of 35.69mg/100g were found in the root bark (30), a higher total iron content than the corresponding leaves and stem bark. The iron content of the decoctions prepared in the traditional way was low.
- PhytoestrogensPhytoestrogens: In animal and in vitro research, some constituents of the extracts of Bridelia ferruginea had estrogenic activity (25).
- Uterotonic herbs and supplementsUterotonic herbs and supplements: In animal research, Bridelia atroviridis had a potent uterotonic action (28).
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Bridelia species/Food Interactions:- Insufficient available evidence.
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Bridelia species/Lab Interactions:- Blood glucoseBlood glucose: According to secondary sources, Bridelia has been used traditionally for its potential antidiabetic effects. Mist bredina is a decoction prepared from Bridelia ferruginea that has purportedly been used for management of diabetes mellitus type 2. Clinical evidence for this therapy is lacking.
- Blood pressureBlood pressure: In animal research, preparations of the leaves of Bridelia atroviridis caused a decrease in arterial pressure (24).
- Coagulation panelCoagulation panel: In animal research, extracts of Bridelia ferruginea exhibited antithrombotic effects (17).
- Heart rateHeart rate: In animal research, preparations of the leaves of Bridelia atroviridis caused a decrease in heart rate (24).
- Iron levelsIron levels: The iron content in the root bark of Bridelia cathartica and its decoction (boiled extract) compared well with those found in edible leafy vegetables (3). Prominent iron contents of 35.69mg/100g were found in the root bark (30), a higher total iron content than the corresponding leaves and stem bark. The iron content of the decoctions prepared in the traditional way was low.
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Copyright © 2011 Natural Standard (www.naturalstandard.com)
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The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.
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